Inflammation in Brain Linked to Autism

Maybe a little closer to understanding a bit more about autism…a new study published in Nature Communications is showing that the brains of people with autism share a common pattern of inflammation related to an overactive immune response.

As discussed in this article, researchers from Johns Hopkins and University of Alabama at Birmingham analyzed the data from autopsied brains of 72 people – 32 of whom had autism – and of those that had autism, they found genes for inflammation permanently activated in certain cells. This was the largest ever study of gene expression in autism.

The inflammation is not likely a root cause of autism, but possibly a consequence of a gene mutation. In order to better understand the inflammation’s effects, researchers will need to determine whether treating it will make an impact on symptoms.

As one of the researchers involved in the study points out, the current findings highlights how much we don’t know about the way our immune systems affect brain activity.

 

Lynsey, Community Manager